Review: HomeDNA Skincare Kit #HomeDNASkincareKit #Skincare #HomeDNA #DNAKit

(product photo courtesy of www.homedna.com)


HomeDNA Skincare Kit $99.00
Not long ago, I was offered the opportunity to take a DNA test that would tell me the answers to my skincare prayers: am I using the right skincare, do I use enough sunscreen, what kind of DNA do I have in terms of aging, am I aging at the the right rate, am I aging too fast and what kinds of skincare do they recommend that I use. All I had to do was swab two cotton swabs on the inside of my cheek for a good continuous 30 seconds (one swab at a time) and do it back and forth, up and down. Then you put the swabs in a sterile envelope that comes with the kit. You fill out all the information on the online account, including the very important barcode (which will follow your account until the end). It takes about 10 business days for them to have the results ready. I had to do it a second time because on the first try they did not get enough DNA from my sample to get enough results, so I would advise swabbing vigorously in the cheeks to make sure enough cheek cells are provided. Once the lab is finished with the DNA results, they will email you or text you and then you can log in to your account and see your results. You can even download the .PDF file to keep it on your computer so that you can refer to it whenever you want.  

With this report you will learn about treatments and ingredients that will help you look your best, to help you achieve your most beautiful looking skin. Use the insights from your genetic information to take better care of your skin every day and help you choose which skin care products to purchase. The test is NOT intended to diagnose, treat, prevent or cure any disease. Results are based on genetics and not your health, diet or the environment. 


Marie Papachatzis' HomeDNA Skincare Report
10/19/2017

Using the unique genetic information collected from the inside of the cheek, the HomeDNA Skin Care DNA Analysis identifies the skin's genetic potential in
seven areas of skin health. To help you understand your outcomes in each category, as well as the skin care recommendations related to them, your results are divided into the following three sections:
  • Understanding Your Genetic Score

  1. Non-ideal: Indicates that you have multiple variants and that the gene's processes may be functioning at a non-ideal level
  2. Global Average: Average score based on the global database
  3. Your Score: Using our proprietary algorithm matrix, the HomeDNA Skin Care Analysis analyzes your markers within each category to place your outcome on the sliding scale. Where you are placed is determined by our scoring system and the global average
  4. Optimal: Indicates that you do not have any genetic variations and that the gene is functioning at an optimal level
  • Your Gene Profile Overview
  1. Non-Ideal: Indicates that you have multiple variants and that thegene's processes may be functioning at a non-ideal level.
  2. Standard: Indicates your genes processes are functioning at a standard level, similar to the averagearound the world.
  3. Optimal: Indicates that you do not have any genetic variations and that the gene is functioning at an optimal level
  • Recommendation Guidelines
  1. Topical Ingredients: These are the most effective ingredients for you based on your genetics. Compare this list with the ingredients in your favorite skin care products, or use it to help you choose new products in thefuture.
  2. Supplement Ingredients: These are the most effective supplement ingredients based on your results. Compare this list with the nutritional supplements you presently take, or use it to help you choose supplements in the future.
  3. Professional Treatments: Skin health may also require professional support.Use this list of treatments to work with a skin-care professional to create the ideal anti-aging for skin program for you.

SKIN CARE DNA | Understanding Tested Categories

Category 1: Fine Lines and Wrinkles
Fine lines and wrinkles are not only formed from a decline in collagen levels but they can also be formed by Advanced Glycation End
(AGE) products. AGEs have the ability to target and stick to collagen and elastin fibers causing them to become rigid and brittle. This is
sometimes likened to rusty springs in a mattress. The effects of glycation at skins cellular level may result in wrinkling, stiff or hardened
collagen fibers, loss of elasticity and compromised skin-barrier functions. The more sugar you consume, whether processed or natural,

the more AGEs are produced.

Category 2: Sun Protection
Your body is equipped with natural responses that help break down photo products once they have penetrated your skin. A
photochemical process helps assist in breaking down UV rays before they can do any major damage.

Skin

Category 3: Sun Sensitivity
Skin sensitivities can create unnecessary stress and trauma to the dermis, leading to tired and aged cells. This type of trauma can lead to
even further sensitivity issues. Understanding if sensitivity may be an issue allows you to better understand the type of things to avoid

and helps keep your skin as stress-free as possible

Category 4: Skin Elasticity
When you are younger, your body has the ability to maintain skin flexibility; but after approximately age 40, skin elasticity can decline due
to a group of enzymes called MMPs. MMPs can increase structural damage to the skin and create imbalances, leading to unstable

collagen support for skin and structure.

Category 5: Pigmentation
Melanin helps protect your skin by absorbing damaging UV rays when you are exposed to the sun. This exposure to sunlight can also
cause your skin to produce more melanin in an attempt to protect the skin. As melanin production increases, our skin begins to tan and

darken. Most irregular skin pigmentation is either caused by an over- or under-production of melanin in the body.

Category 6: Collagen Quality
Collagen makes up approximately 75% of skin, and youthful skin is in large part do to healthy collagen levels. While collagen production
naturally occurs throughout our lives, the quality and quantity vary. As such, many people can experience different levels of skin-aging

attributes based on each individuals level of collagen quality.

Caetogory 7: Skin Anti-oxidants
Premature skin-aging is often a result of free-radical activity within the body. Free radicals are harmful molecules that are produced
naturally from environmental exposures such as tobacco smoke, pollution, and oxygen. The role of antioxidants is to help break down the
damaging effects of free radicals. Antioxidants can also help slow some of the physical signs of aging in order to help preserve your

skins natural glow.


Marie Papachatzis' Score in Categories

Category 1: Fine Lines and Wrinkles
Blood sugar levels can affect the appearance of your skin, in addition to your overall health. Your results indicate you carry few of the gene variations associated with glucose-related fine lines and wrinkles. Excess blood sugar can not only cause a number of health concerns, but can also affect the skin. The body breaks sugar down into many forms and each one requires a set of processors designed to convert sugar into energy. If there is too much sugar in the body or if the body is unable to break it down efficiently, protein molecules can cross-link with the sugar molecules. The result is sugar-protein molecules called Advanced Glycation End Products (AGEs). This cross-linking causes collagen to become fragile and break, ultimately leading to the formation
of fine lines, wrinkles, and thinning skin. 

GENE AT 3P25.2 Anti-Wrinkle Promotion
Optimal: This gene reduces one of the processors that cause collagen fibers to
harden, leading to wrinkles. Your results show that it functions at an
optimal level and that your risk is standard.

GENE AT 1P31.3 Wrinkle Formation Factor
Non-Ideal: This gene helps the body break down excess glucose. Extra glucose can stick to collagen and elastin, causing the collagen to become fragile
and break. This leads to fine lines, wrinkles, and thinning skin. Your
results show that the gene functions at a non-ideal level and that you
have increased risk.

GENE AT 6P21.32 Wrinkle Formation Factor
Optimal: Combined with Wrinkle Formation Factor 1, this gene can speed up the
onset of fine lines and wrinkles. Your results show you have standard
risk associated with the hardening of collagen fibers.

For topical treatments I was told: Your risk in this category is low. To maintain the health of your skin, consider using preventative antioxidants such as vitamins C or E. Always consult a physician or qualified medical professional before beginning any nutritional program.

Category 2: Sun Protection
UV rays from sunlight play a role in skin aging. Your results indicate you carry some of the gene variations that can weaken your skin's natural protection against the sun. The suns UV rays are a major cause of premature skin-aging. Over time, excessive sun exposure (particularly UVA rays) can cause a decline in the visual appearance and overall health of your skin. UVA Rays have very minimal immediate outward effects and their damage may not become visible for many years.

GENE AT 10Q11.23 Sun Protection
Optimal: This gene regulates your skins natural ability to protect against cellular
damage caused by the suns UV rays. Your results show that the gene
functions optimally and that you have standard risk with regard to sun
exposure.

GENE AT 5Q12.1 Sun Protection
Optimal: This gene regulates your skins natural ability to protect against cellular
damage caused by the suns UV rays. Your results show that the gene
functions optimally and that you have standard risk with regard to sun
exposure.

GENE AT 4P16.3 Sun Protection
Optimal:This gene regulates your skins natural ability to protect against cellular
damage caused by the suns UV rays. Your results show that the gene
functions optimally and that you have standard risk with regard to sun
exposure.

Topical Ingredients Recommended: 
  • Ferulic Acid: Helps restore collagen synthesis after UV exposure
  •  Pomegranate: Prevents and reduces sunlight damage (photoaging) after exposure
  •  Pine Bark Extract (Pinus pinasta, Pycnogenol): Reduces redness after UV exposure
  •  Resveratrol: Helps prevent UV damage to skin
  •  Zinc Oxide: Blocks/reduces UV penetration into the skin
Recommended Supplements:
  •  Niacinamide (vitamin B3): Helps repair skin damage when exposed to too much UV light
  •  Vitamin C: Limits the damage caused by UV exposure
  •  Beta Carotene: Provides added skin support against UV exposure
  •  Vitamin D: Ideal if you do not receive regular sun exposure
Professional Treatments:
  • LED Light Therapy: Helps repair DNA damage caused by UV exposure
Category 3: Skin Sensitivity
Five genes were tested for skin sensitivity. Skin sensitivity can be caused by a number of factors, including genetic ones. The results indicate you carry some of the gene variations that may trigger unwanted skin sensitivity issues. Sensitive skin can come in many forms and may be due to climate changes, breakouts, application of fragrance products, and even active skin care. Many skin-sensitivity issues are warning signs that your skin may not be reacting well to these stressors.

GENE AT 7P15.3 Skin Sensitivity
Standard: This gene helps regulate your bodys inflammatory response after cuts, bruises, and exposure to skin irritants. Your results show that you may
be prone to some degree of over-response that can prematurely age
the skin or contribute to conditions such as rosacea, rashes, and raised
bumps.
GENE AT 1Q32.1 Skin Sensitivity
Standard: This gene helps regulate your bodys inflammatory response after cuts, bruises, and exposure to skin irritants. Your results show that you may
be prone to some degree of over-response that can prematurely age
the skin or contribute to conditions such as rosacea, rashes, and raised
bumps. 
GENE AT 6P21.33 Skin Sensitivity
Standard: This gene helps regulate your bodys inflammatory response after cuts, bruises, and exposure to skin irritants. Your results show that you may
be prone to some degree of over-response that can prematurely age
the skin or contribute to conditions such as rosacea, rashes, and raised
bumps.
GENE AT 1Q42.12 Pollution/Fragrance Sensitivity
Optimal: This gene helps break down the chemical compounds that cause skin
sensitivity. Your results show you may experience irritations caused by
pollution, scented products, and skin care ingredients. You may find
that these issues do not manifest until later in life.
GENE AT 6P21.33 Pollution/Fragrance Sensitivity
Optimal: This gene helps regulate your bodys inflammatory response after cuts,
bruises, and exposure to skin irritants. Your results show that you are
not prone to an over-response that can prematurely age the skin or
contribute to conditions such as rosacea, rashes, and raised bumps.

Topical Ingredients Recommendations: 
• Grape Seed Extract: Helps skin retain moisture, supports skin
barrier function, and has antibacterial and anti-inflammatory effects
• Hyaluronic Acid: Ideal moisture agent for sensitive skin
• Resveratrol: Known for antibacterial, anti-acne, and antiinflammatory
properties
• Algae Extract: Provides a protective barrier for the skin and acts
as an anti-inflammatory agent
• Thyme Extract: Protects against environmental stress, including
pollution, and helps calm irritated and inflamed skin
• Centella Asiatica: Promotes healing and has anti-inflammatory
properties

Supplement Ingredients"

• Alpha Lipoic Acid (ALA): Helps reduce inflammatory signaling
proteins
• Fish Oil: Helps reduce inflammatory signaling proteins
• Resveratrol: Helps reduce inflammatory signaling proteins
• Spirulina: Helps reduce inflammatory signaling proteins

Professional Treatments:
• LED Light Therapy: Helps treat red and inflamed skin
• Lactic Acid: Treats breakouts and other skin imperfections

Category 4: Skin Elasticity
Helps identify if MMPs are overactive or if they are at normal levels. Variations that can cause an overactive state may result in weaker collagen support and elasticity issues. Here is where my skin was standard to non-ideal.
Elasticity is the ability of your skin to stretch and return to its original shape. Your results indicate you carry genetic variations that compromise your skins elasticity. Skin Elasticity is the skins ability to stretch and then go back to its original state. As we age,elasticity can decrease due to bodily processors that may weaken the collagen support fibers.

GENE AT 11Q22.2 COLLAGEN FORMATION FACTOR 1, 2, 3
Standard: This marker helps determine the quality of the collagen structure
supporting the skin, which is key to its smoothness, firmness, and
youthfulness. Your results show the marker functions at a less-thanoptimal
level and you may be prone to weakness.

GENE AT 11Q22.2 COLLAGEN FORMATION FACTOR 1, 2, 3
Standard: This marker helps determine the quality of the collagen structure
supporting the skin, which is key to its smoothness, firmness, and
youthfulness. Your results show the marker functions at a less-thanoptimal
level and you may be prone to weakness.

GENE AT 22Q12.3 COLLAGEN DEPRECIATION
Non-Ideal: This gene helps activate robots that damage collagen quality and
structure within the skin. Your results show you have an increased risk
level associated with this activator.

Topical Ingredients: 
• Beta Glucan: Promotes collagen synthesis and skin elasticity
• Centella Asiatica: Promotes cell growth factors to help maintain
skin elasticity
• DMAE Bitartrate: Provides firming benefits to skin beginning to
lose elasticity
• Lipoic Acid: Reduces enzymes responsible for elasticity
breakdown
• White or Green Tea Extract: Reduces enzymes responsible for
elasticity breakdown
• Vitamin E (a-tocopherol form): Protects collagen by reducing
enzymes responsible for elasticity breakdown

Supplement Recommendations:
• Alpha Lipoic Acid (ALA): Helps maintain collagen's structural
formation
• N-Acetyl Cysteine (NAC): Reduces the enzyme responsible for
elasticity breakdown
• Soy Isoflavones: Can help reduce the enzyme responsible for
elasticity breakdown
• Vitamins C and E: Can help reduce the enzyme responsible for
elasticity breakdown
• Whey Protein: Protects collagen and elastin from breakdown
• Lycopene: Protects collagen and elastin from breakdown

Professional Treatments:
• Skin Needling: Increases cellular turnover and collagen production
• LED Light Therapy: Reduces the enzyme responsible for elasticity
breakdown
• Radio Frequency/IR: Increases collagen production

Category 5: Pigmentation 
Helps identify if there is an over- or under-production of melanin that can lead to a complexion with uneven skin pigmentation. Irregular melanin production can be a factor in uneven skin tone and pigmentation. Your results
indicate you carry few of the gene variations that make you prone to irregularities. Uneven skin pigmentation is common across all skin colors, skin types, and ethnic backgrounds. It can be caused by a number of reasons, including exposure to sunlight and genetics. Your skin gets its color from a pigment called melanin. Melanin is an important mechanism in your body and that is designed to help protect your skin from the sun. When skin cells become damaged or unhealthy, melanin production can be affected: this results in varying levels of tanning responses, pigmentation responses and overall skin-health protection. Here I was completely optimal. It's funny because my arms are covered in freckles and I burn like crazy in the sun.

GENE AT 16Q24.3 Tanning Response
Optimal: This gene can affect the switch that controls your skins tanning
response. Your results show your body may be more prone to burning
and sunspots, and less prone to tan. You may be less able to withstand
higher amounts of sun exposure. You may also find that, despite your
sensitivity to the sun, you still tan modestly.

GENE AT 6P25.3 Freckle Factor
Optimal: This gene influences the production of the skin pigment melanin. Your
results show that you have standard risk associated with skin
discolorations and freckling.

Recommendations:
Your risk in this category is low. To maintain the health of your skin, consider using preventative antioxidants such as vitamins C or E. Always consult a physician or qualified medical professional before
beginning any nutritional program.

Category 6: Collagen Quality
The genetic variations tested in this category help assess the quality of the collagen your body produces, as well as other factors that affect your ability to maintain a healthy level of collagen production. Skin collagen levels naturally decline with age. Your results indicate you carry few of the
genetic variations that can speed up the rate at which your collagen quality declines. Your body's ability to maintain healthy collagen levels also appears to be within the ideal range. Collagen is the major protein found in skin. Its fibers create a "scaffold" that provides both strength and structure - collagen is truly what holds the skin together! Collagen also helps give skin its smooth, plump, young appearance. Its production is vital in helping to keep skin full and
firm.

GENE AT 17Q21.33 Collagen Fiber Formation
Optimal: This gene provides instructions for creating the most abundant form of
collagen found in the skin. Your results show that it functions at an
optimal level and that your risk is standard.

GENE AT 2Q32.2 Collagen Fiber Formation
Optimal: This gene provides instructions for creating the secondmost abundant
form of collage in the skin. Your results that show it functions at the optimal level and that your risk is standard.

GENE AT 2Q14.1 Collagen Repair
Standard: This gene regulates the bodys ability to maintain skin barrier
protection, as well as repair damaged collagen tissue. Your results
show that it functions at a less-than-optimal level and that your risk is
partially increased.

GENE AT 6P21.33 Collagen Breakdown
Optimal: This gene helps determine how well your body can form and remodel
collagen. Your results show that your risk is standard.

Recommendations: Your risk in this category is low. To maintain the health of your skin, consider using preventative antioxidants such as vitamins C or E. Always consult a physician or qualified medical professional before
beginning any nutritional program.

Category 7: Skin Anti-Oxidants 
Helps identify any variations that may lead to reduced skin antioxidant protection. Antioxidants help protect your skin against free-radical damage. Your results indicate you carry some of the gene variations that can reduce your skin's natural antioxidant protection. Antioxidants are your true best friends - they are naturally-occurring substances that help reduce the damage to the skin caused by free radicals. Antioxidants are also produced from within the body by key genes to help provide a boost of protection.

GENE AT 16Q.22.1 Anti-Oxidant Factor
Optimal: This gene affects the bodys ability to produce essential antioxidants
that scavenge skin-damaging free radicals. Your results show that your ability to produce these antioxidants is standard.

GENE AT 6Q25.3 Anti-Oxidant Factor
Optimal: This gene affects the bodys ability to produce essential antioxidants
that scavenge skin-damaging free radicals. Your results show that your ability to produce these antioxidants is standard.

GENE AT 3P21.31 Anti-Oxidant Factor
Optimal: This gene affects the bodys ability to produce essential antioxidants
that scavenge skin-damaging free radicals. Your results show that your ability to produce these antioxidants is standard.

GENE AT 11P13 Free Radical Scavenger
Non-Ideal: This gene regulates a free radical scavenger that helps protect skin
cells from oxidative damage. Your results show that it functions at a non-ideal level and that you have increased risk.

GENE AT 16Q22.1 Pollution Protection
Standard: This gene affects the bodys ability to detoxify harmful compounds in
environmental pollutants, such as cigarette smoke and exhaust fumes, that create skin-damaging free radicals. Your results show that it functions at a less-than-optimal level and that you have partially increased risk.

Topical Recommendations:
• Squalene: Reduces the number of skin-damaging free radicals
• Vitamin C: Reduces free radicals
• Vitamin E (a-tocopherol form): Helps protect the skin from free
radical damage
• Resveratrol: Protects cells from oxidative stress and activates the
synthesis of other antioxidants
• Phloretin: Helps protect the skin from free radical damage

Supplements:
• Grape Seed Extract: Scavenges free radicals
• Coenzyme Q10 (CoQ10): Protects cells from free-radical damage
• Resveratrol: Protects cells from oxidative stress and activates the
synthesis of other antioxidants
• Alpha Lipoic Acid (ALA): Protects cells from damage and helps
restore antioxidants, including vitamins C and E

Professional Treatments:
• Mesotherapy: Infuses the skin with antioxidants
• Antioxidant Facials: Infuses the skin with antioxidants


That is the gist of the HomeDNA Skincare Test. To sum up, I had 15 genes at the Optimal level, 7 at the Standard level and and 3 at the Non-Ideal out of 25 genes they tested. That means that genetically, I have pretty good skin. So not only do I take good care of my skin, but I was lucky enough to be born with good skin in the first place. And I can tell this because my mother had good skin, no acne and no wrinkles when she passed away at 55. My father also has good skin, very few wrinkles into his 70's. My goal is to keep taking good care of my skin so that I will not get wrinkles. I will stay out of the sun, because I know I am susceptible to sunburn and freckling. I also know that I am VERY susceptible to anti-oxidant damage. 

I hope you have understood all of this. If there are any questions regarding the results, please contact me at mariepapachatzis@gmail.com. I am available to answer questions about the test the results the genetics, etc. Thank you for reading.

The HomeDNA Skincare Kit can be purchased online at  www.homedna.com/product/homedna-skin-care. Like HomeDNA on Facebook:https://www.facebook.com/HomeDNAbyDDC/; Follow HomeDNA on Twitter:@homednabyddc and Follow HomeDNA on Instagram:https://www.instagram.com/homednabyddc/

Until Next Time~

Marie Papachatzis
I Am THE Makeup Junkie

(This was sent for consideration)








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